By Artisanal Silversmithing & Gemology Review Board
How to avoid contact dermatitis and green skin discoloration: biocompatible jewelry metals, nickel-free certifications, Grade 23 titanium, and solid sterling silver.
Contact dermatitis from trace nickel affects up to 18% of the global population. Choosing biocompatible, certified hypoallergenic jewelry prevents allergic irritation.
1. Metal Biocompatibility Spectrum
Metal Alloy
Allergenic Risk
Key Properties
Implant-Grade Titanium (G23)
0% (Completely Inert)
100% Biocompatible; used in medical implants & body jewelry
Solid 925 Sterling Silver (Nickel-Free)
Extremely Low (< 0.5%)
Alloyed with pure copper; rhodium barrier prevents direct contact
Solid 14K/18K Yellow Gold
Low (< 1.0%)
Pure gold alloyed with copper and silver; zero reactive nickel
Base Metal Brass / Nickel Alloy
Very High (Common Allergen)
Releases nickel ions into skin perspiration, causing eczema rashes